bioinformatics

Events

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Friday, 5th May 2023 | 13:00 h

Chemical Biology Approaches for Tracking and Modulating Circadian Rhythms in Cellular
 Models of Cancer

Am Sandtorkai 74/MS-Teams ROOM: 74.2.07

SPEAKER: Associate Professor Michelle E. Farkas, Department of Chemistry, University of Massachusetts Amherst, USA

SUMMARY: As biology is by nature dynamic, so must be the nature of the tools used for its tracking and modulation. My lab is interested in the development of platforms for following and studying circadian rhythms in the context of cancer. It is appreciated that altered circadian rhythms can contribute to a variety of disease pathologies, including cancer. We are using and developing reporter systems to gain a more detailed picture of oscillations and how they change with cancer type. We are also interested in the use of small molecules and other approaches to directly affect
circadian rhythms.

The seminar is open to interested colleagues and students!

Teams (to join online, please click here)
CONTACT: Prof. Dr. Angela Relόgio


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Thursday, 20th April, 2023 | 13:00 h

ISM Lunchtime Seminar Series

online

The ISM Lunchtime Seminars are online monthly events, which take place on Thursdays, 13:00-13:30h, and are open to all interested colleagues and students. ISM researchers and guest speakers present their work during a 15 min seminar, in the English language, followed by a brief Q&A session. We are happy to announce our next speaker: Prof. Dr. Angela Relgio, Professor for Systems Medicine and Biostatistics

Title: Timing treatment: profiling the circadian clock and optimizing treatment timing in cancer.

Abstract: The biological clock (circadian clock) regulates several aspects of physiology and behaviour and plays avital role in human health. About half of all human genes are rhythmically expressed in at least one tissue, and the time for certain activities such as sleep, exercise, or medicine intake, can be optimized based on the internal circadian rhythm. Recent studies, including work from our group have highlighted a role for clock dysregulation in several hallmarks of cancer related to cell cycle, apoptosis or metabolism. Thus, scheduling anticancer drug administration over 24h may critically impact treatment success in a drug- and patient-specific manner. Our results suggest that, in addition to clock and pharmacological gene expression, the circadian dynamics of translation and cell death, plays an important role in the timing of drug toxicity. Systems biology approaches addressing the personalization of cancer chronotherapies are needed for patient benefit, and can be used to support personalized treatment scheduling, by predicting personalized drug toxicity based on the patient’s gene or protein expression profiles

Please follow the rules below to make these seminars a success:
- Please use your real name while entering the meeting. Participants with cryptic names will not be given access to the seminar.

- Please turn off your microphone while the seminar is taking place.

- Please feel free to ask questions!

Contact information

Please contact
Dr. Deeksha Malhan (deeksha.malhan@medicalschool-hamburg.de) or Dr. Annakarina Mundorf (annakarina.mundorf@medicalschool-hamburg.de) for further information.

Institutions

  • MSH
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Tue, 12th Sep. - Thu, 14th Sep., 2023 | 10:00-18:00 p.m

The German Conference on Bioinformatics (GCB)

DESY Campus, 22607 Hamburg

The German Conference on Bioinformatics (GCB) is an annual, international conference devoted to all areas of bioinformatics and meant as a platform for the whole bioinformatics community. Recent meetings attracted a multinational audience of approx. 250 participants each year.

The conference will take place at the DESY research facility, one of the world’s leading accelerator centres. Besides the talks and poster sessions, ample networking opportunities including a conference dinner, a guided tour through DESY’s accelerator labs, and a company exhibition to connect with industry representatives will be provided. The conference is preceded by a workshop programme on the 11 September 2023.

Looking forward to seeing you in Hamburg!

Submission for poster abstracts is still open

The submission of poster abstracts will close on 7 August 2023.
Submission for lectures is closed.

Institutions

People

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Christian Meyenburg

PhD Candidate, Center for Bioinformatics
christian.meyenburg@uni-hamburg.de
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Deeksha Malhan

Scientific Researcher
Post Doc: Circadian Medicine and Systems Biology
deeksha.malhan@medicalschool-hamburg.de

Sonja Hänzelmann

Team Lead Biomedical Data Analysis
s.haenzelmann@uke.de
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Stephan Seifert

Professor for Chemometrics
stephan.seifert@uni-hamburg.de

Institutions

Universität Hamburg
Adeline Scharfenberg
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Universität Hamburg
Adeline Scharfenberg
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Universität Hamburg
Adeline Scharfenberg
Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein.